Rate this page:

Programmable Voice Quickstart for Python

With just a few lines of code, your Python application can make and receive phone calls with Twilio Programmable Voice.

This Python quickstart will teach you how to do this using our REST API, the Twilio Python helper library, and Python’s Flask microframework to ease development.

In this quickstart, you will learn how to:

  1. Sign up for Twilio and get your first voice-enabled Twilio phone number
  2. Set up your development environment to make and receive phone calls
  3. Make an outbound phone call which plays an MP3
  4. Receive and respond to an inbound phone call which reads a message to the caller using Text to Speech

Prefer to get started by watching a video? Check out our video on how to place and receive phone calls with Python on Youtube.

Show me how it's done!

Sign up for Twilio and get a phone number

If you already have a Twilio account and a voice-enabled Twilio phone number you’re all set here! Log in then feel free to jump to the next step.

Before you can make a phone call from Python, you'll need a Twilio account. Sign up here to get your free trial account or log in to an account you already have.

The next thing you'll need is a voice-capable Twilio phone number. If you don't currently own a Twilio phone number with voice call functionality, you'll need to purchase one. After navigating to the Buy a Number page, check the "Voice" box and click "Search."

Search for a voice-enabled phone number

You’ll then see a list of available phone numbers and their capabilities. Find a number that suits your fancy and click "Buy" to add it to your account.

Purchase a voice-enabled phone number from Twilio

Now that you have a Twilio account and a programmable phone number, you have the basic tools you need to make a phone call.

You could use Twilio's HTTP API to make your phone calls, but we'll make things even more simple by using Twilio's official Python helper library. Let's install that next.

Take me through the setup.

Install Python and the Twilio helper library

If you’ve gone through one of our Python quickstarts already and have Python and the Twilio Python helper library installed, you can skip this step and get straight to making your first phone call.

To make your first phone call with Twilio, you’ll need to have Python and the Twilio Python helper library installed.

Install Python

If you’re using a Mac or Linux machine, you probably already have Python installed. You can check this by opening up a terminal and running the following command:

python --version

You should see something like:

$ python --version
Python 3.9  # Python 3.7+ is okay, too

Windows users can follow this excellent tutorial for installing Python on Windows.

Twilio’s Python SDK only supports Python 3.7+.

Install the Twilio Python helper library

The easiest way to install the library is using pip. Just run this in the terminal:

pip install twilio

If you get the error pip: command not found, you can use easy_install to install the Twilio helper library by running this in your terminal:

easy_install twilio

For a manual installation, you can download the source code (ZIP) for twilio-python and then install the library by running:

python install

in the folder containing the twilio-python library.

And with that, it's time to write some code.

All set! Let's make that phone call.

Make an outgoing phone call with Python

Now that we have Python and twilio-python installed, we can make an outgoing phone call with a single API request from the Twilio phone number we just purchased. Create a new file called and type or paste in this code sample.

Loading Code Sample...

        Make a phone call using Twilio

        This code starts a phone call between the two phone numbers that we pass as arguments. The 'from' number is our Twilio number, and the 'to' number is who we want to call.

        The URL argument points to some TwiML, which tells Twilio what to do next when our recipient answers their phone. This TwiML tells Twilio to read a message using text to speech and then play an MP3.

        Before this code will work, though, we need to edit it a little to work with your Twilio account.

        Replace the placeholder credential values

        Swap the placeholder values for account_sid and auth_token with your personal Twilio credentials.

        Go to and log in. On this page, you’ll find your unique Account SID and Auth Token, which you’ll need any time you send messages through the Twilio Client like this. You can reveal your auth token by clicking on the eyeball icon:

        Reveal Your Auth Token

        Open and replace the values for account_sid and auth_token with your unique values.

        Please note: it's okay to hardcode your credentials when getting started, but you should use environment variables to keep them secret before deploying to production. Check out how to set environment variables for more information.

        Replace the to and from_ phone numbers

        Remember that voice-enabled phone number you bought just a few minutes ago? Go ahead and replace the existing from_ number with that one, making sure to use E.164 formatting:

        [+][country code][phone number including area code]

        Next, replace the to phone number with your mobile phone number. This can be any phone number that can receive calls, but it’s a good idea to test with your phone so that you can see the magic happen! As above, you should use E.164 formatting for this value.

        Save your changes and run the script from your terminal:


        That’s it! Your phone should ring with a call from your Twilio number, and you'll hear our short message for you. 😉

        If you're using a Twilio trial account, outgoing phone calls are limited to phone numbers you have verified with Twilio. Phone numbers can be verified via your Twilio Console's Verified Caller IDs. For other trial account restrictions and limitations, check out our guide on how to work with your free Twilio trial account.

        Next, we’ll learn how to respond to a call made to your Twilio phone number. First, we’ll need to get a Flask server up and running.

        Let's go!

        Install Flask and set up your development environment

        To handle incoming phone calls we'll need a lightweight web application to accept incoming HTTP requests from Twilio. We’ll use Flask for this quickstart, but you can use your choice of web framework to make and receive phone calls from your applications.

        For instructions on setting up Flask on Windows, check out this guide.

        Install pip and virtualenv

        To install Flask and set up our development environment, we’ll need two tools: pip to install Flask and virtualenv to create a unique sandbox for this project. If you already have these tools installed, you can skip to the next section.

        Pip comes pre-packaged with Python 3.4+, so if you’re on a recent version of Python, you don’t need to install anything new. If you’re on an earlier version, never fear: pip is included in virtualenv. So let’s install virtualenv!

        If you’re using Python 2.4, run the following command in your terminal:

        easy_install virtualenv

        If you’re using Python 2.5-2.7, run the following command in your terminal, specifying your version number:

        easy_install-2.7 virtualenv

        Replace the 2.7 with 2.5 or 2.6 if you have that version installed.

        To install virtualenv with Python 3.4+:

        # If you get 'permission denied' errors try running "sudo python" instead of "python"
        pip install virtualenv

        If you get any errors in this step, check out these tips for debugging.

        Create and activate your virtual environment

        Once you have virtualenv installed, use your terminal to navigate to the directory you’re using for this quickstart and create a virtual environment:

        cd Documents/my_quickstart_folder
        virtualenv --no-site-packages .

        Now, activate the virtual environment:

        source bin/activate

        You can verify that your virtualenv is running by looking at your terminal: you should see the name of your enclosing directory. It will look something like this:

        (my_quickstart_folder)USER:~ user$

        To learn more about virtualenv or create a custom environment path, see this thorough guide.

        Install dependencies

        Now we’re ready to install Flask. Create a file called requirements.txt and add the following lines to it:


        Then install both of these packages with pip in your terminal:

        pip install -r requirements.txt

        Test everything from scratch

        First, make sure your virtualenv is activated:

        cd Documents/my_quickstart_folder
        source bin/activate     # On Windows, use .\bin\activate.bat

        Then, create and open a file called and add these lines:

        Loading Code Sample...
              Test your setup with this simple "Hello, World" Flask application

              "Hello, World" Flask application

              Test your setup with this simple "Hello, World" Flask application

              Now it's time to try running it. In your terminal, type:


              You should see:

              $ python
              * Running on

              Navigate to http://localhost:5000 in your browser. You should see a "Hello World!" message. You’re ready to create your first Twilio Programmable Voice app!

              If you encountered any issues or want instructions on setting up your environment with an older Python version (<3.4), check out our full guide to setting up a local Python dev environment.

              All set. How does Twilio talk to my new application?

              Allow Twilio to talk to your Flask application

              We're about to enhance our small Flask application to accept incoming phone calls. But before we do that, we need to make sure Twilio can talk to our local development environment.

              Most Twilio services use webhooks to communicate with your application. When Twilio receives a phone call, for example, it reaches out to a URL in your application for instructions on how to handle the call.

              When you’re working on your Flask application in your development environment, your app is only reachable by other programs on your computer and Twilio won’t be able to talk to it. We need to solve this problem by making your application accessible over the internet.

              While there are a lot of ways to do this, like deploying your application to Heroku or AWS, you'll probably want a less laborious way to test your Twilio application. For a lightweight way to make your app available on the internet, we recommend a tool called ngrok. Once started, ngrok provides a unique URL on the domain which forwards incoming requests to your local development environment.

              How ngrok helps Twilio reach your local server

              If you don’t already use ngrok, head over to their download page and grab the appropriate binary for your operating system. Once downloaded, unzip the package.

              If you're working on a Mac or Linux, you're all set. If you're on Windows, follow our guide on how to install and configure ngrok on Windows. For more info on ngrok, including some great tips and tricks, check out this in-depth blog post.

              Once downloaded, start that Hello World application we made previously:


              Your local application must be running locally for ngrok to do its magic.

              Then open a new terminal tab or window and start ngrok with this command:

              ./ngrok http 5000

              If your local server is running on a different port, replace 5000 with the correct port number.

              You should see output similar to this:

              Ngrok server terminal output

              Copy your public URL from this output and paste it into your browser. You should see your Flask application's "Hello World!" message.

              My server is publicly accessible. Teach me how to receive phone calls!

              Respond to incoming calls with Twilio

              When your Twilio number receives an incoming phone call, it sends an HTTP request to your server asking for instructions on what to do next. Once you receive the request, you can tell Twilio how to respond to the call.

              For this quickstart, we’ll have our Flask app reply to answer the phone call and say a short message to the caller. Open up again and update the code to look like this code sample:

              Loading Code Sample...
                    Respond to an incoming request from Twilio with instructions on how to handle the call

                    Respond to an incoming call with a brief message

                    Respond to an incoming request from Twilio with instructions on how to handle the call

                    Save the file and restart your app with


                    You should now be able to open a web browser to http://localhost:5000/answer. If you view the page source code, you should see the following text:

                    <?xml version="1.0" encoding="UTF-8"?>
                        <Say voice="Polly.Amy">Thank you for calling! Have a great day.</Say>

                    This source code is TwiML XML generated by your code with the help of the Twilio helper library.

                    Double-check that ngrok is still running on localhost with the same port as before. Now Twilio will be able to find your application. There's just one last thing we need before we're ready to call your app: we need to tell Twilio where to send its request.

                    Configure your webhook URL

                    For Twilio to know where to look, you need to configure your Twilio phone number to call your webhook URL whenever a new message comes in.

                    1. Log in to and go to the Console's Numbers page.
                    2. Click on your voice-enabled phone number.
                    3. Find the "Voice & Fax" section. Make sure the "Accept Incoming" selection is set to "Voice Calls." The default "Configure With" selection is what you’ll need: "Webhooks/TwiML...".
                    4. In the "A Call Comes In" section, select "Webhook" and paste in the URL you want to use, appending your '/answer' route:

                    Configure your Voice webhook with your ngrok URL

                    Save your changes - you're ready!

                    Test your application

                    As long as your localhost and the ngrok servers are up and running, we’re ready for the fun part - testing our new Flask application!

                    Make a phone call from your mobile phone to your Twilio phone number. You should see an HTTP request in your ngrok console. Your Flask app will process the incoming request and respond with your TwiML. Then you'll hear your message once the call connects.

                    It worked! All done - what's next?

                    Where to next?

                    Now you know the basics of making and responding to phone calls with Python.

                    Our Flask app here only used the <Say> TwiML verb to read a message to the caller using text to speech, but you can do much more with different TwiML verbs like <Record>, <Gather>, and <Conference>.

                    Check out these pages to learn more:

                    We can't wait to see what you build!

                    Rate this page:

                    Need some help?

                    We all do sometimes; code is hard. Get help now from our support team, or lean on the wisdom of the crowd by visiting Twilio's Stack Overflow Collective or browsing the Twilio tag on Stack Overflow.

                    Loading Code Sample...

                          Thank you for your feedback!

                          Please select the reason(s) for your feedback. The additional information you provide helps us improve our documentation:

                          Sending your feedback...
                          🎉 Thank you for your feedback!
                          Something went wrong. Please try again.

                          Thanks for your feedback!